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butabarbital will lower the extent or influence of doravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.butabarbital will reduce the extent or result of glecaprevir/pibrentasvir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.butabarbital will lower the extent or effect of hydrocortisone by impacting hepatic